/* ===== RESET Y VARIABLES ===== */
:root {
    /* Paleta farmacéutica profesional */
    --primary-dark: #0A2F44;      /* Azul profundo institucional */
    --primary: #1B4B6C;           /* Azul farmacéutico */
    --primary-light: #2C6A8F;     /* Azul más claro */
    --accent: #C44536;             /* Acento terracota (toque cálido) */
    --neutral-100: #FFFFFF;
    --neutral-200: #F5F7FA;
    --neutral-300: #E1E5EC;
    --neutral-400: #9AA6B8;
    --neutral-500: #5A6874;
    --neutral-600: #2C3E4F;
    --neutral-700: #1A2A3A;
    --neutral-800: #0F1A24;
    --neutral-900: #070E14;
    --green-100: #297436;
    
    --shadow-sm: 0 2px 4px rgba(0,0,0,0.02);
    --shadow-md: 0 4px 20px rgba(0,0,0,0.04);
    --shadow-lg: 0 20px 40px rgba(0,0,0,0.06);
    --shadow-inner: inset 0 2px 4px rgba(0,0,0,0.02);
    
    --transition: all 0.2s cubic-bezier(0.4, 0, 0.2, 1);
}

* {
    margin: 0;
    padding: 0;
    box-sizing: border-box;
}

body {
    font-family: 'Inter', sans-serif;
    color: var(--neutral-700);
    line-height: 1.5;
    background-color: var(--neutral-100);
    -webkit-font-smoothing: antialiased;
}

.container {
    max-width: 1480px;
    margin: 0 auto;
    padding: 0 32px;
}

/* ===== TOP BAR INSTITUCIONAL ===== */
.institutional-bar {
    background-color: var(--green-100);
    color: var(--neutral-300);
    font-size: 0.75rem;
    letter-spacing: 0.3px;
    padding: 8px 0;
    border-bottom: 1px solid rgba(255,255,255,0.1);
}

.institutional-bar .container {
    display: flex;
    justify-content: space-between;
    align-items: center;
}

.institutional-left i,
.institutional-right i {
    margin-right: 6px;
    font-size: 0.7rem;
    color: var(--neutral-400);
}

.institutional-right {
    display: flex;
    gap: 12px;
    align-items: center;
}

.separator {
    color: var(--neutral-500);
    font-size: 0.8rem;
}

/* ===== NAVBAR PRINCIPAL ===== */
.navbar {
    background-color: var(--neutral-100);
    border-bottom: 1px solid var(--neutral-300);
    padding: 16px 0;
    position: sticky;
    top: 0;
    z-index: 100;
}

.navbar .container {
    display: flex;
    justify-content: space-between;
    align-items: center;
}

.logo {
    display: flex;
    flex-direction: column;
    line-height: 1;
}

.logo-activz {
    font-family: 'Playfair Display', serif;
    font-size: 1.8rem;
    font-weight: 600;
    color: var(--primary-dark);
    letter-spacing: -0.5px;
}

.logo-sublab {
    font-size: 0.65rem;
    letter-spacing: 2px;
    color: var(--neutral-400);
    text-transform: uppercase;
    margin-top: 2px;
}

.nav-menu {
    display: flex;
    gap: 32px;
    list-style: none;
}

.nav-menu a {
    text-decoration: none;
    color: var(--green-100);
    font-size: 0.85rem;
    font-weight: 500;
    letter-spacing: 0.5px;
    padding: 4px 0;
    border-bottom: 2px solid transparent;
    transition: var(--transition);
}

.nav-menu a:hover,
.nav-menu a.active {
    color: var(--primary);
    border-bottom-color: var(--primary);
}

.nav-actions {
    display: flex;
    gap: 12px;
}

.btn-nav,
.btn-nav-outline {
    text-decoration: none;
    font-size: 0.8rem;
    padding: 8px 16px;
    border-radius: 4px;
    transition: var(--transition);
}

.btn-nav {
    background-color: var(--green-100);
    color: white;
}

.btn-nav:hover {
    background-color: var(--primary-dark);
}

.btn-nav-outline {
    border: 1px solid var(--neutral-300);
    color: var(--neutral-600);
}

.btn-nav-outline:hover {
    border-color: var(--primary);
    color: var(--primary);
}

/* ===== HERO LABORATORIO ===== */
.hero-lab {
    position: relative;
    min-height: 600px;
    background: linear-gradient(135deg, var(--neutral-900) 0%, var(--neutral-800) 100%);
    color: white;
    overflow: hidden;
}

.hero-lab::before {
    content: '';
    position: absolute;
    top: 0;
    left: 0;
    right: 0;
    bottom: 0;
    background-image: url('../IMAGENES/ima1.jpg');
    background-size: cover;
    background-position: center;

    mix-blend-mode: overlay;
}

.hero-overlay {
    position: absolute;
    top: 0;
    left: 0;
    right: 0;
    bottom: 0;
    background:
        linear-gradient(to right, rgba(0, 0, 0, 0.233) 5%, rgba(255, 255, 255, 0.103) 80%),
        radial-gradient(circle at 30% 50%, rgba(106, 204, 61, 0.315) 20%, var(--neutral-900) 250%);
}

.hero-lab .container {
    position: relative;
    z-index: 2;
    height: 100%;
    display: flex;
    align-items: center;
}

.hero-content {
    max-width: 750px;
    padding: 60px 0;
}

.hero-description{


line-height: 1.6;
margin-bottom: 15px;
color: rgba(255,255,255,0.9);

}
.hero-badge {
    display: inline-flex;
    align-items: center;
    gap: 8px;
    background: rgba(255,255,255,0.1);
    backdrop-filter: blur(10px);
    padding: 6px 12px;
    border-radius: 4px;
    font-size: 0.75rem;
    letter-spacing: 0.5px;
    margin-bottom: 24px;
    border: 1px solid rgba(255,255,255,0.2);
}

.hero-title {
    font-size: 3rem;
    font-weight: 600;
    line-height: 1.1;
    margin-bottom: 24px;
    font-family: 'Playfair Display', serif;
}

.text-highlight {
    color: #E6B17E;
    border-bottom: 2px solid rgba(230, 177, 126, 0.3);
}

.hero-subtitle {
    font-size: 1rem;
    line-height: 1.6;
    color: var(--neutral-300);
    margin-bottom: 32px;
    max-width: 700px;
}

.hero-stats {
    display: flex;
    gap: 32px;
    margin-bottom: 40px;
}

.stat-item {
    display: flex;
    flex-direction: column;
}

.stat-number {
    font-size: 2rem;
    font-weight: 600;
    color: white;
    line-height: 1;
}

.stat-label {
    font-size: 0.75rem;
    color: var(--neutral-400);
    letter-spacing: 0.5px;
    text-transform: uppercase;
}

.hero-buttons {
    display: flex;
    gap: 16px;
}

.btn-primary {
    display: inline-flex;
    align-items: center;
    gap: 8px;
    background-color: white;
    color: var(--neutral-900);
    text-decoration: none;
    padding: 14px 28px;
    font-weight: 500;
    font-size: 0.9rem;
    border-radius: 4px;
    transition: var(--transition);
}

.btn-primary:hover {
    background-color: var(--neutral-200);
    transform: translateY(-2px);
}

.btn-secondary {
    display: inline-flex;
    align-items: center;
    gap: 8px;
    background-color: transparent;
    color: white;
    text-decoration: none;
    padding: 14px 28px;
    font-weight: 500;
    font-size: 0.9rem;
    border-radius: 4px;
    border: 1px solid rgba(255,255,255,0.3);
    transition: var(--transition);
}

.btn-secondary:hover {
    border-color: white;
    background-color: rgba(255,255,255,0.05);
}

/* ===== BREADCRUMB ===== */
.breadcrumb {
    padding: 24px 0;
    background-color: var(--neutral-200);
    border-bottom: 1px solid var(--neutral-300);
}

.breadcrumb ul {
    display: flex;
    align-items: center;
    gap: 8px;
    list-style: none;
}

.breadcrumb a {
    text-decoration: none;
    color: var(--neutral-500);
    font-size: 0.8rem;
    transition: var(--transition);
}

.breadcrumb a:hover {
    color: var(--primary);
}

.breadcrumb .active {
    color: var(--neutral-700);
    font-weight: 500;
    font-size: 0.8rem;
}

.breadcrumb i {
    font-size: 0.6rem;
    color: var(--neutral-400);
}

/* ===== FILTROS CIENTÍFICOS ===== */
.filters-section {
    padding: 48px 0 24px;
    background-color: var(--neutral-100);
}

.filters-header {
    text-align: center;
    margin-bottom: 32px;
}

.filters-header h2 {
    font-family: 'Playfair Display', serif;
    font-size: 2rem;
    color: var(--neutral-800);
    margin-bottom: 8px;
}

.filters-header p {
    color: var(--neutral-500);
    font-size: 0.9rem;
}

.filters-grid {
    display: flex;
    justify-content: center;
    gap: 12px;
    flex-wrap: wrap;
}

.filter-btn {
    display: flex;
    align-items: center;
    gap: 8px;
    padding: 12px 24px;
    background-color: var(--neutral-200);
    border: 1px solid var(--neutral-300);
    border-radius: 4px;
    font-size: 0.85rem;
    font-weight: 500;
    color: var(--neutral-600);
    cursor: pointer;
    transition: var(--transition);
}

.filter-btn i {
    font-size: 1rem;
    color: var(--primary-light);
}

.filter-count {
    background-color: var(--neutral-300);
    padding: 2px 8px;
    border-radius: 20px;
    font-size: 0.7rem;
    margin-left: 4px;
}

.filter-btn:hover {
    background-color: var(--neutral-300);
    border-color: var(--primary);
}

.filter-btn.active {
    background-color: var(--primary);
    border-color: var(--primary);
    color: white;
}

.filter-btn.active i,
.filter-btn.active .filter-count {
    color: white;
    background-color: rgba(255,255,255,0.2);
}

/* ===== GRID DE PRODUCTOS ===== */
.products-grid-section {
    padding: 24px 0 80px;
    background-color: var(--neutral-200);
}

.products-grid {
    display: grid;
    grid-template-columns: repeat(auto-fill, minmax(350px, 1fr));
    gap: 24px;
}

.product-card {
    background-color: white;
    border-radius: 8px;
    overflow: hidden;
    box-shadow: var(--shadow-md);
    border: 1px solid var(--neutral-300);
    transition: var(--transition);
}

.product-card:hover {
    box-shadow: var(--shadow-lg);
    transform: translateY(-4px);
}

.product-badge {
    position: absolute;
    top: 16px;
    left: 16px;
    background-color: var(--accent);
    color: white;
    padding: 4px 12px;
    border-radius: 4px;
    font-size: 0.7rem;
    font-weight: 600;
    letter-spacing: 0.5px;
}

.product-header {
    position: relative;
    padding: 24px;
    background: linear-gradient(135deg, var(--primary) 0%, var(--primary-dark) 100%);
    color: white;
}

.product-icon {
    font-size: 2.5rem;
    margin-bottom: 16px;
}

.product-header h3 {
    font-size: 1.8rem;
    font-weight: 600;
    margin-bottom: 4px;
    font-family: 'Playfair Display', serif;
}

.product-subtitle {
    font-size: 0.85rem;
    opacity: 0.9;
    font-weight: 400;
}

.product-body {
    padding: 24px;
}

.product-mechanism {
    background-color: var(--neutral-200);
    padding: 16px;
    border-radius: 6px;
    margin-bottom: 20px;
    border-left: 3px solid var(--primary);
}

.mechanism-label {
    display: block;
    font-size: 0.7rem;
    text-transform: uppercase;
    letter-spacing: 1px;
    color: var(--neutral-500);
    margin-bottom: 8px;
}

.mechanism-text {
    font-size: 0.9rem;
    line-height: 1.6;
    color: var(--neutral-700);
}

.product-benefits {
    list-style: none;
    margin-bottom: 20px;
}

.product-benefits li {
    display: flex;
    align-items: center;
    gap: 10px;
    padding: 8px 0;
    border-bottom: 1px solid var(--neutral-300);
    font-size: 0.9rem;
}

.product-benefits li:last-child {
    border-bottom: none;
}

.product-benefits i {
    color: var(--primary);
    font-size: 0.8rem;
}

.product-studies {
    background-color: rgba(27, 75, 108, 0.05);
    padding: 16px;
    border-radius: 6px;
    margin-bottom: 20px;
    display: none;
}

.product-studies.show {
    display: block;
    animation: slideDown 0.3s ease;
}

.study-item {
    display: flex;
    align-items: center;
    gap: 12px;
    padding: 8px 0;
    font-size: 0.85rem;
    border-bottom: 1px dashed var(--neutral-300);
}

.study-item:last-child {
    border-bottom: none;
}

.study-item i {
    color: var(--accent);
    font-size: 0.8rem;
}

.product-footer {
    padding: 20px 24px 24px;
    border-top: 1px solid var(--neutral-300);
    display: flex;
    justify-content: space-between;
    align-items: center;
}

.product-rating {
    display: flex;
    align-items: center;
    gap: 8px;
}

.stars {
    color: #FFB800;
    letter-spacing: 1px;
}

.rating-number {
    font-weight: 600;
    color: var(--neutral-700);
}

.reviews-count {
    font-size: 0.75rem;
    color: var(--neutral-500);
}

.product-actions {
    display: flex;
    gap: 8px;
}

.btn-study {
    padding: 8px 16px;
    background-color: transparent;
    border: 1px solid var(--neutral-300);
    border-radius: 4px;
    font-size: 0.8rem;
    cursor: pointer;
    transition: var(--transition);
}

.btn-study:hover {
    border-color: var(--primary);
    color: var(--primary);
}

.btn-buy {
    padding: 8px 20px;
    background-color: var(--primary);
    border: none;
    border-radius: 4px;
    color: white;
    font-size: 0.8rem;
    cursor: pointer;
    transition: var(--transition);
}

.btn-buy:hover {
    background-color: var(--primary-dark);
}

/* ===== SECCIÓN DE CIENCIA ===== */
.science-section {
    padding: 80px 0;
    background-color: white;
}

.section-label {
    display: inline-block;
    font-size: 0.7rem;
    letter-spacing: 2px;
    color: var(--primary);
    text-transform: uppercase;
    margin-bottom: 12px;
}

.science-header {
    text-align: center;
    max-width: 800px;
    margin: 0 auto 48px;
}

.science-header h2 {
    font-family: 'Playfair Display', serif;
    font-size: 2.2rem;
    color: var(--neutral-800);
    margin-bottom: 16px;
}

.science-header p {
    color: var(--neutral-500);
    font-size: 0.95rem;
    line-height: 1.6;
}

.science-cards {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(280px, 1fr));
    gap: 24px;
}

.science-card {
    padding: 32px;
    background-color: var(--neutral-200);
    border-radius: 8px;
    transition: var(--transition);
}

.science-card:hover {
    background-color: white;
    box-shadow: var(--shadow-md);
}

.card-icon {
    width: 48px;
    height: 48px;
    background-color: var(--primary);
    color: white;
    border-radius: 8px;
    display: flex;
    align-items: center;
    justify-content: center;
    margin-bottom: 20px;
}

.card-icon i {
    font-size: 1.5rem;
}

.science-card h3 {
    font-size: 1.2rem;
    margin-bottom: 12px;
    color: var(--neutral-800);
}

.science-card p {
    color: var(--neutral-600);
    font-size: 0.9rem;
    line-height: 1.6;
    margin-bottom: 20px;
}

.card-link {
    text-decoration: none;
    color: var(--primary);
    font-size: 0.85rem;
    font-weight: 500;
    display: inline-flex;
    align-items: center;
    gap: 6px;
}

/* ===== ASESORES CIENTÍFICOS ===== */
.advisors-section {
    padding: 80px 0;
    background-color: var(--neutral-200);
}

.advisors-header {
    text-align: center;
    margin-bottom: 48px;
}

.advisors-header h2 {
    font-family: 'Playfair Display', serif;
    font-size: 2rem;
    color: var(--neutral-800);
}

.advisors-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(300px, 1fr));
    gap: 30px;
    max-width: 800px;
    margin: 0 auto;
}

.advisor-card {
    display: flex;
    gap: 20px;
    background-color: white;
    padding: 24px;
    border-radius: 8px;
    box-shadow: var(--shadow-md);
}

.advisor-image {
    width: 80px;
    height: 80px;
    border-radius: 50%;
    overflow: hidden;
}

.advisor-image img {
    width: 100%;
    height: 100%;
    object-fit: cover;
}

.advisor-info h3 {
    font-size: 1.1rem;
    margin-bottom: 4px;
    color: var(--neutral-800);
}

.advisor-title {
    font-size: 0.8rem;
    color: var(--primary);
    font-weight: 500;
    margin-bottom: 4px;
}

.advisor-affiliation {
    font-size: 0.75rem;
    color: var(--neutral-500);
    margin-bottom: 4px;
}

.advisor-publications {
    font-size: 0.7rem;
    color: var(--neutral-400);
}

/* ===== PUBLICACIONES ===== */
.publications-section {
    padding: 80px 0;
    background-color: white;
}

.publications-header {
    text-align: center;
    margin-bottom: 48px;
}

.publications-header h2 {
    font-family: 'Playfair Display', serif;
    font-size: 2rem;
    color: var(--neutral-800);
    max-width: 600px;
    margin: 0 auto;
}

.publications-list {
    max-width: 700px;
    margin: 0 auto;
}

.publication-item {
    display: flex;
    gap: 24px;
    padding: 20px;
    border-bottom: 1px solid var(--neutral-300);
}

.pub-year {
    font-size: 1.2rem;
    font-weight: 600;
    color: var(--primary);
    min-width: 60px;
}

.pub-content h3 {
    font-size: 1rem;
    margin-bottom: 8px;
    color: var(--neutral-800);
}

.pub-authors {
    font-size: 0.8rem;
    color: var(--neutral-600);
    margin-bottom: 4px;
}

.pub-journal {
    font-size: 0.75rem;
    color: var(--neutral-500);
    margin-bottom: 8px;
    font-style: italic;
}

.pub-link {
    text-decoration: none;
    color: var(--primary);
    font-size: 0.75rem;
    display: inline-flex;
    align-items: center;
    gap: 4px;
}

.publications-footer {
    text-align: center;
    margin-top: 40px;
}

.btn-outline {
    display: inline-flex;
    align-items: center;
    gap: 8px;
    padding: 12px 32px;
    border: 1px solid var(--primary);
    color: var(--primary);
    text-decoration: none;
    border-radius: 4px;
    font-size: 0.9rem;
    transition: var(--transition);
}

.btn-outline:hover {
    background-color: var(--primary);
    color: white;
}

/* ===== FOOTER ===== */
.footer-lab {
    background-color: var(--neutral-800);
    color: white;
    padding: 60px 0 20px;
}

.footer-main {
    display: grid;
    grid-template-columns: 2fr repeat(3, 1fr);
    gap: 40px;
    margin-bottom: 40px;
}

.footer-col .footer-logo {
    margin-bottom: 16px;
}

.footer-logo .logo-activz {
    color: white;
    font-size: 1.5rem;
}

.footer-logo .logo-sublab {
    color: var(--neutral-400);
}

.footer-description {
    color: var(--neutral-400);
    font-size: 0.85rem;
    line-height: 1.6;
    margin-bottom: 20px;
}

.footer-certifications {
    display: flex;
    gap: 16px;
    font-size: 1.5rem;
    color: var(--neutral-400);
}

.footer-col h4 {
    font-size: 0.9rem;
    letter-spacing: 1px;
    margin-bottom: 20px;
    color: white;
}

.footer-col ul {
    list-style: none;
}

.footer-col ul li {
    margin-bottom: 12px;
}

.footer-col ul a {
    text-decoration: none;
    color: var(--neutral-400);
    font-size: 0.8rem;
    transition: var(--transition);
}

.footer-col ul a:hover {
    color: white;
}

.footer-col ul i {
    width: 20px;
    color: var(--primary-light);
}

.footer-bottom {
    padding-top: 20px;
    border-top: 1px solid var(--neutral-600);
    display: flex;
    justify-content: space-between;
    align-items: center;
    font-size: 0.7rem;
    color: var(--neutral-500);
}

.legal-links {
    display: flex;
    gap: 20px;
}

.legal-links a {
    text-decoration: none;
    color: var(--neutral-500);
}

.legal-links a:hover {
    color: var(--neutral-300);
}

/* ===== ANIMACIONES ===== */
@keyframes slideDown {
    from {
        opacity: 0;
        transform: translateY(-10px);
    }
    to {
        opacity: 1;
        transform: translateY(0);
    }
}

@keyframes fadeIn {
    from {
        opacity: 0;
        transform: translateY(20px);
    }
    to {
        opacity: 1;
        transform: translateY(0);
    }
}

.product-card {
    animation: fadeIn 0.5s ease;
}

/* ===== RESPONSIVE ===== */
@media (max-width: 1024px) {
    .footer-main {
        grid-template-columns: repeat(2, 1fr);
    }
}

@media (max-width: 768px) {
    .navbar .container {
        flex-direction: column;
        gap: 16px;
    }
    
    .nav-menu {
        flex-wrap: wrap;
        justify-content: center;
    }
    
    .hero-title {
        font-size: 2.5rem;
    }
    
    .hero-stats {
        flex-wrap: wrap;
    }
    
    .hero-buttons {
        flex-direction: column;
    }
    
    .institutional-right {
        display: none;
    }
    
    .institutional-left {
        width: 100%;
        text-align: center;
    }
    
    .filters-grid {
        flex-direction: column;
        align-items: stretch;
    }
    
    .filter-btn {
        justify-content: center;
    }
    
    .footer-main {
        grid-template-columns: 1fr;
    }
    
    .footer-bottom {
        flex-direction: column;
        gap: 16px;
        text-align: center;
    }
    
    .legal-links {
        justify-content: center;
    }
}

@media (max-width: 480px) {
    .container {
        padding: 0 20px;
    }
    
    .hero-title {
        font-size: 2rem;
    }
    
    .hero-stats {
        flex-direction: column;
        gap: 16px;
    }
    
    .publication-item {
        flex-direction: column;
        gap: 8px;
    }
    
    .advisor-card {
        flex-direction: column;
        align-items: center;
        text-align: center;
    }
}



/* ===== LÍNEAS DE INVESTIGACIÓN CLÍNICA ===== */
/* ===== LÍNEAS DE INVESTIGACIÓN CLÍNICA ===== */
.clinical-lines-section {
    padding: 80px 0;
    background: linear-gradient(135deg, var(--neutral-100) 0%, var(--neutral-200) 100%);
    border-bottom: 1px solid var(--neutral-300);
}

.clinical-lines-header {
    text-align: center;
    max-width: 700px;
    margin: 0 auto 56px;
}

.clinical-lines-header h2 {
    font-family: 'Playfair Display', serif;
    font-size: 2.2rem;
    color: var(--neutral-800);
    margin: 16px 0;
}

.clinical-lines-header p {
    color: var(--neutral-500);
    font-size: 0.95rem;
    line-height: 1.6;
}

.clinical-lines-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(250px, 1fr)); /* Reducido de 280px a 250px */
    gap: 20px; /* Reducido de 30px a 20px */
}

.clinical-line-card {
    background-color: white;
    padding: 20px; /* Reducido de 32px a 20px */
    border-radius: 8px;
    box-shadow: var(--shadow-md);
    border: 1px solid var(--neutral-300);
    transition: var(--transition);
    display: flex;
    flex-direction: column;
}

.clinical-line-card:hover {
    box-shadow: var(--shadow-lg);
    transform: translateY(-4px);
    border-color: var(--primary-light);
}

.line-icon {
    height: 200px; /* Reducido drásticamente de 380px a 180px */
    background-color: rgba(27, 75, 108, 0.1);
    color: var(--primary);
    border-radius: 8px; /* Reducido de 12px a 8px */
    display: flex;
    align-items: center;
    justify-content: center;
    margin-bottom: 16px; /* Reducido de 24px a 16px */
}

.line-icon img {
    max-width: 90%; /* Para asegurar que la imagen no se desborde */
    max-height: 100%;
    object-fit: contain;
}

.line-icon i {
    font-size: 1.5rem; /* Reducido de 2rem a 1.5rem */
}

.clinical-line-card h3 {
    font-size: 1.2rem; /* Reducido ligeramente de 1.3rem */
    color: var(--neutral-800);
    margin-bottom: 8px; /* Reducido de 12px a 8px */
    font-weight: 600;
}

.line-description {
    color: var(--neutral-600);
    font-size: 0.85rem; /* Reducido de 0.9rem */
    line-height: 1.5; /* Ajustado de 1.6 */
    margin-bottom: 16px; /* Reducido de 20px a 16px */
    flex-grow: 1;
}

.line-products {
    display: flex;
    flex-wrap: wrap;
    gap: 6px; /* Reducido de 8px a 6px */
    margin-bottom: 16px; /* Reducido de 24px a 16px */
    border-top: 1px solid var(--neutral-300);
    padding-top: 16px; /* Reducido de 20px a 16px */
}

.product-tag {
    background-color: var(--neutral-200);
    color: var(--neutral-700);
    padding: 3px 10px; /* Reducido de 4px 12px */
    border-radius: 4px;
    font-size: 0.7rem; /* Reducido de 0.75rem */
    font-weight: 500;
    letter-spacing: 0.3px;
    border: 1px solid var(--neutral-300);
}

.line-link {
    text-decoration: none;
    color: var(--primary);
    font-size: 0.8rem; /* Reducido de 0.85rem */
    font-weight: 500;
    display: inline-flex;
    align-items: center;
    gap: 6px;
    margin-top: auto;
    transition: var(--transition);
}

.line-link:hover {
    color: var(--primary-dark);
    gap: 10px;
}

/* ===== SECCIÓN CIENCIA NRF2 Y TRIFECTA ===== */
.nrf2-science-section {
    padding: 80px 0;
    background-color: var(--neutral-100);
    border-bottom: 1px solid var(--neutral-300);
}

.science-description {
    max-width: 700px;
    margin: 0 auto;
    color: var(--neutral-500);
    font-size: 1rem;
    line-height: 1.6;
}

/* Grid de 2 columnas para conceptos NRF2 */
.nrf2-grid {
    display: grid;
    grid-template-columns: repeat(2, 1fr);
    gap: 30px;
    margin-bottom: 60px;
}

.nrf2-card {
    background-color: var(--neutral-200);
    border-radius: 8px;
    overflow: hidden;
    box-shadow: var(--shadow-sm);
    border: 1px solid var(--neutral-300);
    transition: var(--transition);
}

.nrf2-card:hover {
    box-shadow: var(--shadow-md);
    transform: translateY(-2px);
}

.nrf2-card .card-header {
    padding: 24px;
    background: linear-gradient(135deg, var(--green-100) 0%, var(--primary-dark) 100%);
    color: white;
    display: flex;
    align-items: center;
    gap: 15px;
}

.nrf2-card .card-header i {
    font-size: 2rem;
    color: rgba(255,255,255,0.9);
}

.nrf2-card .card-header h3 {
    font-size: 1.3rem;
    font-weight: 500;
    margin: 0;
    font-family: 'Playfair Display', serif;
}

.nrf2-card .card-body {
    padding: 24px;
}

.nrf2-card .card-body p {
    color: var(--neutral-600);
    font-size: 0.95rem;
    line-height: 1.7;
    margin-bottom: 16px;
}

.nrf2-card .card-body p:last-child {
    margin-bottom: 20px;
}

.nrf2-card .card-body strong {
    color: var(--primary-dark);
    font-weight: 600;
}

/* Bloque de Respaldo Científico */
.scientific-background {
    background: linear-gradient(135deg, var(--green-100) 10% , var(--neutral-900) 100%);
    border-radius: 8px;
    padding: 40px;
    margin-bottom: 60px;
    color: white;
    position: relative;
    overflow: hidden;
}

.scientific-background::before {
    content: '\f2db';
    font-family: 'Font Awesome 6 Free';
    font-weight: 900;
    position: absolute;
    right: -20px;
    bottom: -20px;
    font-size: 150px;
    color: rgba(255,255,255,0.03);
    transform: rotate(15deg);
    pointer-events: none;
}

.background-header {
    display: flex;
    align-items: center;
    gap: 15px;
    margin-bottom: 25px;
}

.background-header i {
    font-size: 2.5rem;
    color: var(--accent);
}

.background-header h3 {
    font-size: 1.8rem;
    font-weight: 500;
    font-family: 'Playfair Display', serif;
    margin: 0;
    color: white;
}

.background-content p {
    color: var(--neutral-300);
    font-size: 1rem;
    line-height: 1.7;
    margin-bottom: 20px;
    max-width: 800px;
}

.background-content p:last-child {
    margin-bottom: 0;
}

.background-footer {
    margin-top: 30px;
}

.background-footer .btn-outline {
    border-color: rgba(255,255,255,0.3);
    color: white;
    background-color: transparent;
}

.background-footer .btn-outline:hover {
    background-color: white;
    color: var(--neutral-900);
    border-color: white;
}

/* Sección TRIFECTA */
.trifecta-section {
    margin-top: 40px;
}

.trifecta-header {
    text-align: center;
    margin-bottom: 48px;
}

.trifecta-header h3 {
    font-family: 'Playfair Display', serif;
    font-size: 2rem;
    color: var(--neutral-800);
    margin: 16px 0 12px;
}

.trifecta-grid {
    display: grid;
    grid-template-columns: repeat(3, 1fr);
    gap: 30px;
    margin-bottom: 40px;
}

.trifecta-item {
    background-color: var(--neutral-200);
    padding: 32px 24px;
    border-radius: 8px;
    text-align: center;
    border: 1px solid var(--neutral-300);
    transition: var(--transition);
}

.trifecta-item:hover {
    background-color: white;
    box-shadow: var(--shadow-md);
    transform: translateY(-4px);
}

.trifecta-item .item-icon {
    width: 70px;
    height: 70px;
    background: linear-gradient(135deg, var(--green-100) 0%, var(--primary-dark) 100%);
    color: white;
    border-radius: 50%;
    display: flex;
    align-items: center;
    justify-content: center;
    margin: 0 auto 20px;
}

.trifecta-item .item-icon i {
    font-size: 2rem;
}

.trifecta-item h4 {
    font-size: 1.5rem;
    color: var(--neutral-800);
    margin-bottom: 6px;
    font-family: 'Playfair Display', serif;
}

.item-tagline {
    color: var(--primary);
    font-size: 0.85rem;
    font-weight: 500;
    letter-spacing: 0.5px;
    text-transform: uppercase;
    margin-bottom: 16px;
}

.item-description {
    color: var(--neutral-600);
    font-size: 0.9rem;
    line-height: 1.6;
    margin: 0;
}

.trifecta-synergy {
    background-color: var(--neutral-200);
    border-radius: 8px;
    padding: 40px;
    border-left: 4px solid var(--accent);
    margin-top: 30px;
}

.synergy-content h4 {
    font-size: 1.3rem;
    color: var(--neutral-800);
    margin-bottom: 20px;
    font-family: 'Playfair Display', serif;
}

.synergy-content p {
    color: var(--neutral-600);
    font-size: 1rem;
    line-height: 1.7;
    margin-bottom: 20px;
}

.synergy-content ul {
    list-style: none;
    margin-bottom: 20px;
}

.synergy-content ul li {
    display: flex;
    align-items: center;
    gap: 10px;
    padding: 8px 0;
    font-size: 0.95rem;
    color: var(--neutral-700);
}

.synergy-content ul li i {
    color: var(--green-100);
    font-size: 1rem;
}

/* Responsive para la nueva sección */
@media (max-width: 1024px) {
    .nrf2-grid,
    .trifecta-grid {
        grid-template-columns: repeat(2, 1fr);
    }
    
    .trifecta-grid {
        gap: 20px;
    }
}

@media (max-width: 768px) {
    .nrf2-grid,
    .trifecta-grid {
        grid-template-columns: 1fr;
    }
    
    .scientific-background {
        padding: 30px;
    }
    
    .background-header h3 {
        font-size: 1.5rem;
    }
    
    .trifecta-synergy {
        padding: 30px;
    }
}

@media (max-width: 480px) {
    .nrf2-card .card-header {
        flex-direction: column;
        text-align: center;
    }
    
    .trifecta-item {
        padding: 24px 16px;
    }
}

/* ===== VERSIÓN COMPACTA ===== */
.nrf2-grid {
    display: grid;
    grid-template-columns: repeat(2, 1fr);
    gap: 25px;
    margin: 40px 0;
}

.nrf2-card-compact {
    background: white;
    border-radius: 12px;
    padding: 30px;
    box-shadow: var(--shadow-md);
    border: 1px solid var(--neutral-300);
    transition: all 0.3s ease;
    position: relative;
    overflow: hidden;
}

.nrf2-card-compact::before {
    content: '';
    position: absolute;
    top: 0;
    left: 0;
    width: 4px;
    height: 100%;
    background: linear-gradient(135deg, var(--primary), var(--accent));
}

.nrf2-card-compact:hover {
    transform: translateY(-5px);
    box-shadow: var(--shadow-lg);
}

.card-icon-large {
    width: 70px;
    height: 70px;
    background: linear-gradient(135deg, var(--green-100) 0%, var(--primary-dark) 100%);
    color: white;
    border-radius: 50%;
    display: flex;
    align-items: center;
    justify-content: center;
    margin-bottom: 5px;
    font-size: 2rem;
}

.nrf2-card-compact h3 {
    font-size: 1.5rem;
    margin-bottom: 12px;
    color: var(--neutral-800);
}

.card-summary {
    color: var(--neutral-600);
    line-height: 1.6;
    margin-bottom: 20px;
    font-size: 0.95rem;
}

.card-stats {
    display: flex;
    gap: 20px;
    margin-bottom: 25px;
    padding: 15px 0;
    border-top: 1px solid var(--neutral-300);
    border-bottom: 1px solid var(--neutral-300);
}

.card-stats span {
    font-size: 0.85rem;
    color: var(--neutral-600);
}

.card-stats strong {
    color: var(--primary);
    font-size: 1.1rem;
}

.btn-card {
    display: inline-flex;
    align-items: center;
    gap: 8px;
    color: var(--primary);
    text-decoration: none;
    font-weight: 500;
    font-size: 0.9rem;
    transition: all 0.2s;
}

.btn-card:hover {
    gap: 12px;
    color: var(--primary-dark);
}

/* Bloque científico compacto */
.scientific-background-compact {
    background: linear-gradient(135deg, var(--neutral-800) 0%, var(--neutral-900) 100%);
    border-radius: 12px;
    padding: 25px 30px;
    margin: 40px 0;
    display: flex;
    align-items: center;
    justify-content: space-between;
    color: white;
}

.scientific-content {
    display: flex;
    align-items: center;
    gap: 20px;
}

.scientific-content i {
    font-size: 2.5rem;
    color: var(--accent);
}

.scientific-content h4 {
    font-size: 1.2rem;
    margin-bottom: 5px;
}

.scientific-content p {
    color: var(--neutral-300);
    font-size: 0.9rem;
    margin: 0;
}

.btn-outline-small {
    padding: 10px 20px;
    border: 1px solid rgba(255,255,255,0.3);
    border-radius: 6px;
    color: white;
    text-decoration: none;
    font-size: 0.85rem;
    display: inline-flex;
    align-items: center;
    gap: 8px;
    transition: all 0.2s;
}

.btn-outline-small:hover {
    background: white;
    color: var(--neutral-900);
}

/* Grid de productos compacto */
.trifecta-mini-grid {
    display: grid;
    grid-template-columns: repeat(3, 1fr);
    gap: 20px;
    margin-top: 30px;
}

.trifecta-mini-card {
    background: white;
    border-radius: 10px;
    overflow: hidden;
    box-shadow: var(--shadow-md);
    transition: all 0.3s ease;
}

.trifecta-mini-card:hover {
    transform: translateY(-5px);
    box-shadow: var(--shadow-lg);
}

.mini-card-header {
    padding: 20px;
    text-align: center;
    color: white;
}

.mini-card-header i {
    font-size: 2rem;
    margin-bottom: 10px;
}

.mini-card-header h4 {
    font-size: 1.2rem;
    margin: 0;
}

.trifecta-mini-card p {
    padding: 15px;
    text-align: center;
    font-size: 0.85rem;
    color: var(--neutral-600);
    margin: 0;
}

.mini-card-link {
    display: block;
    padding: 12px;
    text-align: center;
    background: var(--neutral-200);
    color: var(--primary);
    text-decoration: none;
    font-size: 0.85rem;
    font-weight: 500;
    transition: all 0.2s;
}

.mini-card-link:hover {
    background: #95989b;
    color: white;
}

@media (max-width: 768px) {
    .nrf2-grid,
    .trifecta-mini-grid {
        grid-template-columns: 1fr;
    }
    
    .scientific-background-compact {
        flex-direction: column;
        text-align: center;
        gap: 20px;
    }
    
    .scientific-content {
        flex-direction: column;
    }
}

/* Botón principal para catálogo */
.bttn-primary {
    margin: 20px 44%;
  font-family: 'Source Sans Pro', sans-serif;
  font-size: 15px;
  letter-spacing: 1.5px;
  text-transform: uppercase;
  display: inline-flex;
  align-items: center;
  justify-content: center;
  gap: 12px;
  min-width: 200px;
  font-weight: 600;
  padding: 16px 32px;
  border: 2px solid var(--green-100, #297436);
  border-radius: 4px;
  position: relative;
  color: var(--green-100, #297436);
  text-decoration: none;
  background: transparent;
  transition: color 0.3s ease;
  z-index: 1;
  cursor: pointer;
}

.bttn-primary i {
  font-size: 1.2em;
  transition: transform 0.3s ease;
}

.bttn-primary:hover {
  color: #FFF;
}

.bttn-primary:hover i {
  transform: translateX(6px);
}

.bttn-primary::before {
  content: '';
  position: absolute;
  top: 0;
  left: 50%;
  right: 50%;
  bottom: 0;
  background-color: var(--green-100, #297436);
  transition: left 0.4s ease, right 0.4s ease;
  z-index: -1;
}

.bttn-primary:hover::before {
  left: 0;
  right: 0;
}

/* Versión específica para catálogo (puedes ajustar tamaño) */
.bttn-catalogo {
  min-width:120px;
  padding: 18px 32px;
  font-size: 15px;
}